⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29319837 | 0.77 | — | — | |
| SCHEMBL30748834 | 0.77 | PGR (0.33) | — | |
| SCHEMBL29195972 | 0.77 | PGR (0.33) | — | |
| SCHEMBL30749125 | 0.76 | PGR (0.35) | — | |
| SCHEMBL31627002 | 0.70 | PIM1 (0.30) | — | |
| SCHEMBL30748876 | 0.67 | KCNH2 (0.32) | — | |
| SCHEMBL29195979 | 0.67 | KCNH2 (0.32) | — | |
| SCHEMBL21492262 | 0.67 | — | — | |
| SCHEMBL16446622 | 0.66 | MAPK14 (0.37) | — | |
| SCHEMBL29319840 | 0.64 | SRC (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239808-A1 | INHIBITING UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) | FORMA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | US | disclosed |