Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 6/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22399995 | 1.00 | AHCY (0.57) | AHCYADORA2BP2RY1ADORA3ENPP1 | |
| SCHEMBL22399999 | 0.89 | AHCY (0.73) | AHCYADORA2BP2RY1ADORA3 | |
| SCHEMBL19503479 | 0.89 | AHCY (0.73) | AHCYADORA2BP2RY1ADORA3 | |
| SCHEMBL19503898 | 0.89 | AHCY (0.73) | AHCYADORA2BP2RY1ADORA3 | |
| SCHEMBL19503474 | 0.89 | AHCY (0.49) | AHCYP2RY1ADORA3ENPP1P2RY12 | |
| SCHEMBL16290177 | 0.88 | AHCY (0.56) | AHCYADORA2BP2RY1ENPP1P2RY12 | |
| SCHEMBL12330956 | 0.88 | AHCY (0.56) | AHCYADORA2BP2RY1ENPP1P2RY12 | |
| SCHEMBL29319896 | 0.83 | PDE4D (0.62) | AHCYADORA2BADORA3PNPLMNA | |
| SCHEMBL9311442 | 0.81 | AHCY (0.83) | AHCYADORA2BPNPLMNATP53 | |
| SCHEMBL19503889 | 0.78 | P2RY1 (0.47) | P2RY1ENPP1P2RY12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445368-B1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |