Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MME | P08473 | 6/20 | 0.53 |
| ▸ | ACE | P12821 | 5/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068729 | 1.00 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL25626773 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL11206052 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL5404763 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL11206050 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL232608 | 0.80 | MME (0.60) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL1642433 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL928741 | 0.79 | — | — | |
| SCHEMBL23408865 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL22652505 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146920-A1 | DRUG CONJUGATES FOR THE TREATMENT OF OCULAR DISORDERS | ASCENDIS PHARMA OPHTHALMOLOGY DIVISION A/S (DK) | 2024-07-11 | — | — | WO | disclosed |