Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.39 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31248557 | 0.88 | PDE4B (0.40) | PDE4BEEDRBBP4SUZ12EZH2 | |
| SCHEMBL29320340 | 0.88 | PDE4B (0.40) | PDE4BEEDRBBP4SUZ12EZH2 | |
| SCHEMBL31056950 | 0.88 | PDE4B (0.40) | PDE4BEEDRBBP4SUZ12EZH2 | |
| SCHEMBL31263683 | 0.87 | USP30 (0.43) | PDE4BEEDRBBP4SUZ12EZH2 | |
| SCHEMBL30988665 | 0.83 | NR1H2 (0.43) | PDE4BNR1H2PKMMAPK1GPR119 | |
| SCHEMBL5763372 | 0.83 | NR1H2 (0.43) | PDE4BNR1H2PKMMAPK1GPR119 | |
| SCHEMBL31248547 | 0.83 | NR1H2 (0.43) | PDE4BNR1H2PKMMAPK1GPR119 | |
| SCHEMBL31248558 | 0.83 | NR1H2 (0.43) | PDE4BNR1H2PKMMAPK1GPR119 | |
| SCHEMBL29320165 | 0.79 | XIAP (0.34) | ALDH1A1 | |
| SCHEMBL6994594 | 0.78 | GSK3B (0.42) | PDE4BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |