Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CPS1 | P31327 | 2/20 | 0.31 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323240 | 0.89 | CA12 (0.39) | XIAPBIRC2TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL30109209 | 0.83 | XIAP (0.41) | XIAPBIRC2ALDH1A1KDM4EMEN1 | |
| SCHEMBL31269556 | 0.83 | XIAP (0.41) | XIAPBIRC2ALDH1A1KDM4EMEN1 | |
| SCHEMBL30109126 | 0.83 | XIAP (0.41) | XIAPBIRC2ALDH1A1KDM4EMEN1 | |
| SCHEMBL29324631 | 0.81 | ALDH1A1 (0.36) | XIAPBIRC2TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL29320350 | 0.81 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL31056638 | 0.79 | CD274 (0.34) | XIAPBIRC2ALDH1A1KDM4EMEN1 | |
| SCHEMBL29320160 | 0.79 | PDE4B (0.39) | ALDH1A1 | |
| SCHEMBL31056475 | 0.79 | TMEM97 (0.42) | TMEM97SIGMAR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL31056754 | 0.76 | HTR4 (0.34) | XIAPBIRC2TMEM97SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |