Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29320583 | 0.83 | BCL9 (0.39) | LMNABCL9CTNNB1 | |
| SCHEMBL29318781 | 0.81 | BCL9 (0.41) | BCL9CTNNB1 | |
| SCHEMBL29320372 | 0.81 | BCL9 (0.41) | BCL9CTNNB1 | |
| SCHEMBL29319614 | 0.80 | BCL9 (0.39) | BCL9CTNNB1 | |
| SCHEMBL29320312 | 0.78 | BCL9 (0.39) | LMNABCL9CTNNB1 | |
| SCHEMBL29320294 | 0.78 | BCL9 (0.39) | BCL9CTNNB1 | |
| SCHEMBL29320518 | 0.77 | BCL9 (0.37) | BCL9CTNNB1 | |
| SCHEMBL29318865 | 0.73 | DRD3 (0.41) | PROKR1ALDH1A1BCL9CTNNB1 | |
| SCHEMBL29318784 | 0.72 | BCL9 (0.66) | PROKR1BCL9CTNNB1 | |
| SCHEMBL30350398 | 0.72 | BCL9 (0.66) | PROKR1BCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |