Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 8/20 | 0.39 |
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29318865 | 0.90 | DRD3 (0.41) | BCL9CTNNB1DRD3DRD2DRD4 | |
| SCHEMBL29320372 | 0.87 | BCL9 (0.41) | BCL9CTNNB1DRD3DRD2DRD4 | |
| SCHEMBL29318885 | 0.86 | DRD3 (0.42) | BCL9CTNNB1DRD3DRD2DRD4 | |
| SCHEMBL29318790 | 0.85 | BCL9 (0.44) | BCL9CTNNB1DRD3DRD2DRD4 | |
| SCHEMBL29320312 | 0.85 | BCL9 (0.39) | BCL9CTNNB1DRD3DRD2DRD4 | |
| SCHEMBL29320294 | 0.85 | BCL9 (0.39) | BCL9CTNNB1DRD3DRD2DRD4 | |
| SCHEMBL29320583 | 0.83 | BCL9 (0.39) | BCL9CTNNB1DRD3DRD2DRD4 | |
| SCHEMBL29320229 | 0.82 | PPARA (0.42) | BCL9CTNNB1DRD3DRD2DRD4 | |
| SCHEMBL29320417 | 0.81 | PROKR1 (0.41) | BCL9CTNNB1 | |
| SCHEMBL29319057 | 0.81 | BCL9 (0.38) | BCL9CTNNB1DRD3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |