Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929315 | 0.83 | CSNK1D (0.37) | MAPK14CSNK1DMAP4K4MAPK9CSNK1A1 | |
| SCHEMBL2929628 | 0.80 | MAPK14 (0.49) | MAPK14CSNK1DMAP4K4MAPK9CSNK1A1 | |
| SCHEMBL29332356 | 0.80 | MAPK14 (0.48) | MAPK14CSNK1DMAP4K4MAPK9CSNK1A1 | |
| SCHEMBL1384383 | 0.78 | MAPK9 (0.46) | MAPK14CSNK1DMAP4K4MAPK9CSNK1A1 | |
| SCHEMBL1384559 | 0.77 | MAPK14 (0.46) | MAPK14CSNK1DMAP4K4MAPK9CSNK1A1 | |
| SCHEMBL1384398 | 0.76 | CSNK1D (0.43) | MAPK14CSNK1DMAP4K4MAPK9CSNK1A1 | |
| SCHEMBL1385618 | 0.76 | MAPK14 (0.42) | MAPK14CSNK1DMAP4K4MAPK9CSNK1A1 | |
| SCHEMBL1386713 | 0.75 | PTGS2 (0.38) | MAPK14CSNK1DMAP4K4MAPK9CSNK1A1 | |
| SCHEMBL1384371 | 0.73 | MAPK14 (0.43) | MAPK14CSNK1DMAP4K4MAPK9CSNK1A1 | |
| SCHEMBL1383998 | 0.73 | MAPK14 (0.47) | MAPK14CSNK1DMAP4K4MAPK9CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611131-B1 | PYRAZOLOPYRIDINE DERIVATES | PALAU PHARMA SA (ES) | 2010-09-15 | — | — | EP | disclosed |