Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31467009 | 0.80 | PARP1 (0.40) | PARP1MEN1MAPTTSHRHTT | |
| SCHEMBL26984319 | 0.80 | PARP1 (0.40) | PARP1MEN1MAPTTSHRHTT | |
| SCHEMBL31056598 | 0.79 | SLC6A2 (0.37) | PARP1SLC6A2SLC6A4CTSLCTSB | |
| SCHEMBL29323708 | 0.79 | SLC6A2 (0.37) | PARP1SLC6A2SLC6A4CTSLCTSB | |
| SCHEMBL29322208 | 0.76 | PARP1 (0.38) | PARP1 | |
| SCHEMBL5328082 | 0.74 | PARP1 (0.53) | PARP1 | |
| SCHEMBL4516849 | 0.74 | SLC6A2 (0.44) | PARP1SLC6A2SLC6A4MEN1MAPT | |
| SCHEMBL31056540 | 0.73 | SLC6A2 (0.38) | PARP1SLC6A2SLC6A4CTSLCTSB | |
| SCHEMBL29321033 | 0.73 | SLC6A2 (0.38) | PARP1SLC6A2SLC6A4CTSLCTSB | |
| SCHEMBL31056959 | 0.73 | SLC6A2 (0.34) | PARP1SLC6A2SLC6A4CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |