Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26984319 | 1.00 | PARP1 (0.40) | PARP1PDK2PDK4KDM4EALDH1A1 | |
| SCHEMBL29322206 | 0.80 | PARP1 (0.37) | PARP1NPSR1DRD2DRD4DRD3 | |
| SCHEMBL5328082 | 0.79 | PARP1 (0.53) | PARP1KDM4E | |
| SCHEMBL3500989 | 0.75 | PARP1 (0.44) | PARP1PDK2PDK4KDM4EALDH1A1 | |
| SCHEMBL29322208 | 0.74 | PARP1 (0.38) | PARP1 | |
| SCHEMBL12599964 | 0.74 | KDM4E (0.38) | PARP1PDK2PDK4KDM4EALDH1A1 | |
| SCHEMBL13312001 | 0.73 | PARP1 (0.43) | PARP1KDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL3630293 | 0.72 | SRC (0.50) | PARP1KDM4EALDH1A1NPSR1HSD17B10 | |
| SCHEMBL12620162 | 0.70 | KDM4E (0.37) | PARP1PDK2PDK4KDM4EALDH1A1 | |
| SCHEMBL14774736 | 0.70 | ALOX5 (0.43) | PARP1KDM4EALDH1A1HSD17B10DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677716-A | Pharmaceutical compositions comprising WRN helicase inhibitors | 维维迪恩医疗公司 | 2025-03-21 | — | — | CN | disclosed |