Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 3/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | KYNU | Q16719 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323242 | 0.89 | SYK (0.60) | SYKMAPTPPARACTSSKLK7 | |
| SCHEMBL29323038 | 0.89 | SYK (0.59) | SYKMAPTPPARACTSSKLK7 | |
| SCHEMBL7424195 | 0.88 | SYK (0.58) | SYKMAPTPPARACTSSSIRT2 | |
| SCHEMBL7425992 | 0.88 | SYK (0.58) | SYKMAPTPPARACTSSSIRT2 | |
| SCHEMBL22574551 | 0.88 | SYK (0.64) | SYKMAPTPPARACTSSSIRT2 | |
| SCHEMBL22574549 | 0.88 | SYK (0.64) | SYKMAPTPPARACTSSSIRT2 | |
| SCHEMBL21900170 | 0.88 | SIRT2 (0.60) | SYKMAPTCTSSSIRT2SIRT1 | |
| SCHEMBL21900169 | 0.88 | SIRT2 (0.60) | SYKMAPTCTSSSIRT2SIRT1 | |
| SCHEMBL19295560 | 0.88 | SIRT2 (0.60) | SYKMAPTCTSSSIRT2SIRT1 | |
| SCHEMBL31072474 | 0.87 | MAPT (0.57) | SYKMAPTPPARACTSSKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239771-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | TAXIS PHARMACEUTICALS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239771-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | ABCB11, ABCB1, SLC47A1 | SYK 4472/4885MAPT 4313/4885PPARA 3159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.