⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24363986 | 0.75 | BRD4 (0.34) | — | |
| SCHEMBL18269369 | 0.70 | GRM5 (0.30) | — | |
| SCHEMBL29296173 | 0.69 | LMNA (0.33) | — | |
| SCHEMBL29296185 | 0.66 | — | — | |
| SCHEMBL18269368 | 0.65 | — | — | |
| SCHEMBL13101106 | 0.62 | — | — | |
| SCHEMBL29296288 | 0.62 | — | — | |
| SCHEMBL10005358 | 0.61 | — | — | |
| SCHEMBL12032502 | 0.61 | — | — | |
| SCHEMBL15395030 | 0.61 | GRM5 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |