Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 20/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.60 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.60 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.60 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.60 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20778905 | 0.93 | GABRA5 (0.69) | GABRA5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL29323905 | 0.88 | GABRA5 (0.78) | GABRA5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL20778813 | 0.88 | GABRA5 (0.79) | GABRA5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL20778812 | 0.82 | GABRA5 (0.74) | GABRA5 | |
| SCHEMBL29323855 | 0.82 | GABRA5 (0.76) | GABRA5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL22149683 | 0.81 | GABRA5 (0.87) | GABRA5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL4157298 | 0.81 | GABRA5 (1.00) | GABRA5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL20778806 | 0.81 | GABRA5 (0.77) | GABRA5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL2923588 | 0.77 | GABRA5 (1.00) | GABRA5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL4162112 | 0.76 | GABRA5 (1.00) | GABRA5GABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675845-B1 | NOVEL GAMMA AMINOBUTYRIC ACID TYPE A RECEPTOR MODULATORS FOR MOOD DISORDERS | UNIV MARYLAND (US) | 2024-07-17 | — | — | EP | disclosed |