Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30179301 | 0.90 | DRD2 (0.44) | DRD2 | |
| SCHEMBL28967717 | 0.90 | DRD2 (0.44) | DRD2 | |
| SCHEMBL29323098 | 0.85 | DRD2 (0.62) | DRD2 | |
| SCHEMBL29324093 | 0.85 | DRD2 (0.50) | DRD2HTR1A | |
| SCHEMBL30179173 | 0.83 | DRD2 (0.48) | DRD2MAPTNPSR1HTR1A | |
| SCHEMBL29322785 | 0.83 | DRD2 (0.48) | DRD2MAPTNPSR1HTR1A | |
| SCHEMBL29324627 | 0.82 | DRD2 (0.61) | DRD2MAPTHTR1A | |
| SCHEMBL28967715 | 0.82 | DRD2 (0.44) | DRD2HRH3 | |
| SCHEMBL30179518 | 0.82 | DRD2 (0.44) | DRD2HRH3 | |
| SCHEMBL29324116 | 0.82 | DRD2 (0.51) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400504-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CN) | 2024-07-17 | — | — | EP | disclosed |