Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29322671 | 0.93 | KDM4E (0.45) | KDM4EL3MBTL1AURKAJAK2ABL1 | |
| SCHEMBL6571189 | 0.81 | KDM4E (0.40) | KDM4EL3MBTL1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL3409820 | 0.78 | KCNH3 (0.38) | CYP3A4HTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL19451193 | 0.78 | KCNH3 (0.38) | CYP3A4HTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL20423605 | 0.78 | KCNH3 (0.38) | CYP3A4HTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL13311297 | 0.78 | KCNH3 (0.38) | CYP3A4HTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL29025343 | 0.78 | KCNH3 (0.38) | CYP3A4HTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL5150650 | 0.76 | SMYD2 (0.39) | KDM4ECYP3A4HTTSMN1; SMN2LMNA | |
| SCHEMBL21810823 | 0.76 | SMYD2 (0.39) | KDM4ECYP3A4HTTSMN1; SMN2LMNA | |
| SCHEMBL3833607 | 0.75 | CYP3A4 (0.37) | KDM4ECYP3A4HTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400491-A1 | NOVEL LIPIDS USED FOR NUCLEIC ACID DELIVERY AND LIPID NANOPARTICLE COMPOSITION | Themedium Therapeutics Co., Ltd (CN) | 2024-07-17 | — | — | EP | disclosed |