⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2134249 | 0.74 | — | — | |
| SCHEMBL27490888 | 0.69 | — | — | |
| SCHEMBL14846362 | 0.69 | — | — | |
| SCHEMBL28750008 | 0.69 | — | — | |
| SCHEMBL28432496 | 0.67 | — | — | |
| SCHEMBL14278510 | 0.67 | — | — | |
| SCHEMBL28942397 | 0.65 | — | — | |
| SCHEMBL30712743 | 0.65 | — | — | |
| SCHEMBL28537221 | 0.65 | — | — | |
| SCHEMBL11720477 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238264-A1 | INHIBITORS OF SARM1 NADASE ACTIVITY AND USES THEREOF | DISARM THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |