Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23054687 | 1.00 | POLRMT (0.46) | POLRMTDOT1LSTING1MAP4K4 | |
| SCHEMBL29323062 | 1.00 | POLRMT (0.46) | POLRMTDOT1LSTING1MAP4K4 | |
| SCHEMBL16708491 | 0.89 | POLRMT (0.39) | POLRMTDOT1LSTING1MAP4K4 | |
| SCHEMBL16708508 | 0.89 | POLRMT (0.46) | POLRMTDOT1LSTING1MAP4K4 | |
| SCHEMBL19779087 | 0.89 | POLRMT (0.46) | POLRMTDOT1LSTING1MAP4K4 | |
| SCHEMBL19768739 | 0.89 | POLRMT (0.46) | POLRMTDOT1LSTING1MAP4K4 | |
| Hydrochloric Acid SCHEMBL25392678 | 0.88 | POLRMT (0.45) | POLRMTDOT1LSTING1MAP4K4 | |
| Hydrochloric Acid SCHEMBL25392672 | 0.87 | POLRMT (0.45) | POLRMTDOT1LSTING1MAP4K4 | |
| SCHEMBL29323450 | 0.84 | POLRMT (0.34) | POLRMT | |
| SCHEMBL23054692 | 0.83 | POLRMT (0.32) | POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238323-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES | EMORY UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238323-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES | MTAP, PNP, SARS1 | POLRMT 108/4885DOT1L 2034/4885STING1 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.