Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21373474 | 0.75 | HMGCR (0.37) | HMGCRPTGS2PTPN7TDP1RECQL | |
| SCHEMBL30088546 | 0.66 | PTPN7 (0.48) | HMGCRPTPN7TDP1RECQLALDH1A1 | |
| SCHEMBL9547952 | 0.66 | — | — | |
| SCHEMBL14760329 | 0.66 | HMGCR (0.42) | HMGCRPTPN7TDP1RECQLALDH1A1 | |
| SCHEMBL10900390 | 0.66 | HMGCR (0.46) | HMGCRPTGS2PTPN7TDP1RECQL | |
| SCHEMBL998012 | 0.64 | HMGCR (0.40) | HMGCRPTGS2PTPN7TDP1RECQL | |
| Bicarbonate SCHEMBL4957571 | 0.64 | PTPN7 (0.52) | HMGCRPTPN7TDP1RECQLALDH1A1 | |
| SCHEMBL29833624 | 0.64 | HMGCR (0.44) | HMGCRPTPN7TDP1RECQLALDH1A1 | |
| SCHEMBL16594552 | 0.64 | TSHR (0.43) | HMGCRPTGS2PTPN7TDP1RECQL | |
| SCHEMBL1101649 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151425-A1 | COMPOUNDS AND METHOD FOR TREATING HIV INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-07-18 | — | — | WO | disclosed |