Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 10/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056939 | 1.00 | TMEM97 (0.46) | TMEM97SIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL29324569 | 0.91 | TMEM97 (0.47) | TMEM97SIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL31056921 | 0.90 | TMEM97 (0.48) | TMEM97SIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL31056583 | 0.90 | TMEM97 (0.46) | TMEM97SIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL31056771 | 0.88 | TMEM97 (0.45) | TMEM97SIGMAR1PDE4B | |
| SCHEMBL31056814 | 0.85 | TMEM97 (0.42) | TMEM97SIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL31056568 | 0.84 | PDE4B (0.42) | TMEM97SIGMAR1PDK1PDK2PDK3 | |
| SCHEMBL8248090 | 0.76 | TMEM97 (0.55) | TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL206142 | 0.75 | TMEM97 (0.52) | TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL29324155 | 0.74 | NR1H2 (0.47) | PDK2PDK4PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |