Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 7/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.36 |
| ▸ | CALCA | P06881 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.35 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324569 | 0.84 | TMEM97 (0.47) | PDE4BPDK2PDK4 | |
| SCHEMBL28961486 | 0.80 | NR1H2 (0.48) | NR1H2NR1H3USP30CA12CA1 | |
| SCHEMBL29326266 | 0.79 | NR1H2 (0.47) | NR1H2NR1H3EEDRBBP4SUZ12 | |
| SCHEMBL31056568 | 0.78 | PDE4B (0.42) | NR1H2NR1H3PDE4BPDK2PDK4 | |
| SCHEMBL29321333 | 0.77 | NR1H2 (0.47) | NR1H2NR1H3PDE4BCALCATACR1 | |
| SCHEMBL31056552 | 0.77 | CFB (0.40) | — | |
| SCHEMBL31056740 | 0.77 | NR1H2 (0.49) | NR1H2NR1H3PDE4BPDK2PDK4 | |
| SCHEMBL29321108 | 0.76 | NR1H2 (0.46) | NR1H2NR1H3PDE4BCALCATACR1 | |
| SCHEMBL29320347 | 0.76 | ALDH1A1 (0.38) | NR1H2NR1H3PDE4B | |
| SCHEMBL29323240 | 0.75 | CA12 (0.39) | CA12CA1CA2CA7PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |