Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PTPRC | P08575 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13652528 | 0.81 | ALDH1A1 (0.66) | ALDH1A1HTTHPGDKMT2AMAPT | |
| SCHEMBL13745573 | 0.80 | HTT (1.00) | ALDH1A1HTTHPGDKMT2AMAPT | |
| SCHEMBL1948433 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HTTKMT2AMAPTNLRP1 | |
| SCHEMBL14570553 | 0.79 | HTT (0.73) | ALDH1A1HTTHPGDKMT2AMAPT | |
| SCHEMBL29245711 | 0.78 | ALDH1A1 (0.61) | ALDH1A1HTTHPGDKMT2AMAPT | |
| SCHEMBL2095026 | 0.77 | GLA (0.69) | ALDH1A1HTTHPGDKMT2AMAPT | |
| SCHEMBL5346635 | 0.77 | ALDH1A1 (0.74) | ALDH1A1HTTHPGDKMT2AMAPT | |
| SCHEMBL12646737 | 0.76 | KDM4E (0.62) | ALDH1A1HTTKMT2AMAPTGAA | |
| SCHEMBL19921053 | 0.76 | ALDH1A1 (0.69) | ALDH1A1HTTHPGDKMT2AMAPT | |
| SCHEMBL2091569 | 0.75 | GLA (0.71) | ALDH1A1HTTHPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149992-A1 | IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS | UNIVERSITY OF DUNDEE (GB) | 2024-07-18 | — | — | WO | disclosed |