SCHEMBL29324514

SCHEMBL29324514

O=C1CCC(c2noc3c(CCCN4CCNCC4)cccc23)C(=O)N1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 13/20 0.41
CRBN Q96SW2 13/20 0.41
SIGMAR1 Q99720 2/20 0.35
CCNE2 O96020 1/20 0.35
CDK4 P11802 1/20 0.35
PRKACA P17612 1/20 0.35
PRKACG P22612 1/20 0.35
PRKACB P22694 1/20 0.35
CCND1 P24385 1/20 0.35
CCNE1 P24864 1/20 0.35
CDK2 P24941 1/20 0.35
CAMK2B Q13554 1/20 0.35
CAMK2G Q13555 1/20 0.35
CAMK2D Q13557 1/20 0.35
CAMK2A Q9UQM7 1/20 0.35
DRD2 P14416 1/20 0.34
HTR1A P08908 2/20 0.34
HTR2A P28223 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324512 0.83 DDB1 (0.48) DDB1CRBN
SCHEMBL29321737 0.78 ALDH1A1 (0.38) DDB1CRBNCCNE2CDK4CCND1
SCHEMBL31323635 0.75 DDB1 (0.45) DDB1CRBN
SCHEMBL31323627 0.75 DDB1 (0.38) DDB1CRBNDRD2HTR1AHTR2A
SCHEMBL29324735 0.74 DDB1 (0.42) DDB1CRBNSIGMAR1
SCHEMBL31323681 0.74 DDB1 (0.41) DDB1CRBN
SCHEMBL31323623 0.74 DDB1 (0.41) DDB1CRBNDRD2
SCHEMBL23117078 0.73 CRBN (0.49) DDB1CRBNHTR1AHTR2A
SCHEMBL31443853 0.73 CRBN (0.49) DDB1CRBN
SCHEMBL31323586 0.73 DDB1 (0.49) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed