SCHEMBL29324602

SCHEMBL29324602

CC(=O)c1cccc(NC(=O)OC(C)(C)C)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.52
ALOX15 P16050 1/20 0.45
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.45
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
PDK1 Q15118 1/20 0.41
PDK2 Q15119 1/20 0.41
PDK3 Q15120 1/20 0.41
PDK4 Q16654 1/20 0.41
LMNA P02545 2/20 0.41
POLB P06746 1/20 0.41
METAP1 P53582 1/20 0.41
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
BRD9 Q9H8M2 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5812852 0.88 KDM4E (0.51) RXFP1ALOX15MAPK1HSD17B10RAB9A
SCHEMBL29324603 0.86 RXFP1 (0.46) RXFP1ALOX15MAPK1HSD17B10RAB9A
SCHEMBL29992092 0.86 RXFP1 (0.59) RXFP1RAB9ANPC1MEN1HTT
SCHEMBL15368377 0.86 RXFP1 (0.59) RXFP1RAB9ANPC1MEN1HTT
SCHEMBL31167247 0.84 RXFP1 (0.54) RXFP1RAB9ANPC1MEN1HTT
SCHEMBL1172444 0.80 RXFP1 (0.44) RXFP1RAB9ALMNAPOLBMETAP1
SCHEMBL28220374 0.80 RXFP1 (0.47) RXFP1RAB9ANPC1PDK1PDK2
SCHEMBL14243354 0.80 NPC1 (0.46) RXFP1RAB9ANPC1MEN1HTT
SCHEMBL27847969 0.79 LMNA (0.44) RXFP1ALOX15MAPK1HSD17B10NPC1
SCHEMBL909725 0.79 HSD17B10 (0.56) RXFP1ALOX15MAPK1HSD17B10RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed