Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.30 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17807816 | 0.72 | KDM5B (0.31) | KDM5B | |
| SCHEMBL27386322 | 0.71 | PARP16 (0.31) | PARP16PARP3 | |
| SCHEMBL29338632 | 0.71 | PARP1 (0.38) | TYK2 | |
| SCHEMBL25737805 | 0.68 | MKNK2 (0.42) | TYK2PARP16PARP3 | |
| SCHEMBL7754905 | 0.68 | LMNA (0.31) | PARP16PARP3 | |
| SCHEMBL21477550 | 0.67 | — | — | |
| SCHEMBL3636926 | 0.67 | PTGS1 (0.33) | — | |
| SCHEMBL8180707 | 0.67 | HPGD (0.35) | TYK2PARP16PARP3 | |
| SCHEMBL18239105 | 0.67 | CHEK1 (0.33) | KDM5B | |
| SCHEMBL12120570 | 0.67 | KDM5B (0.30) | KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151833-A1 | SPIRO DERIVATIVES AS M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS, LLC (US) | 2024-07-18 | — | — | WO | disclosed |