Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 5/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326196 | 0.92 | CYP1A1 (0.44) | CYP1A1CYP1B1ERCC5FEN1KDM4E | |
| SCHEMBL29326467 | 0.90 | ERCC5 (0.44) | CYP1A1CYP1B1ERCC5FEN1KDM4E | |
| SCHEMBL29326453 | 0.90 | CYP1A1 (0.47) | CYP1A1CYP1B1ERCC5FEN1KDM4E | |
| SCHEMBL29326656 | 0.89 | CYP1A1 (0.51) | CYP1A1CYP1B1ERCC5FEN1KDM4E | |
| SCHEMBL29326183 | 0.89 | ERCC5 (0.43) | CYP1A1CYP1B1ERCC5FEN1KDM4E | |
| SCHEMBL29326200 | 0.89 | CYP1A1 (0.43) | CYP1A1CYP1B1ERCC5FEN1KDM4E | |
| SCHEMBL29326194 | 0.88 | ERCC5 (0.40) | CYP1A1CYP1B1ERCC5FEN1KDM4E | |
| SCHEMBL27192316 | 0.88 | CYP1A1 (0.44) | CYP1A1CYP1B1ERCC5FEN1KDM4E | |
| SCHEMBL29326215 | 0.87 | ERCC5 (0.41) | CYP1A1CYP1B1ERCC5FEN1KDM4E | |
| SCHEMBL29326188 | 0.87 | CYP1A1 (0.53) | CYP1A1CYP1B1ERCC5FEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | CYP1A1 882/4885CYP1B1 1007/4885ERCC5 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.