Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 5/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326658 | 0.90 | ERCC5 (0.39) | CYP1A1CYP1B1ERCC5FEN1CYP1A2 | |
| SCHEMBL29326162 | 0.89 | CYP1A1 (0.53) | CYP1A1CYP1B1ERCC5FEN1CYP1A2 | |
| SCHEMBL27377455 | 0.89 | P2RX7 (0.42) | CYP1A1CYP1B1ERCC5FEN1CYP1A2 | |
| SCHEMBL29326663 | 0.86 | HSD17B10 (0.41) | CYP1A1CYP1B1ERCC5FEN1CYP1A2 | |
| SCHEMBL29326188 | 0.85 | CYP1A1 (0.53) | CYP1A1CYP1B1ERCC5FEN1CYP1A2 | |
| SCHEMBL29326207 | 0.84 | ERCC5 (0.36) | CYP1A1CYP1B1ERCC5FEN1CYP1A2 | |
| SCHEMBL29326467 | 0.83 | ERCC5 (0.44) | CYP1A1CYP1B1ERCC5FEN1CYP1A2 | |
| SCHEMBL29326196 | 0.83 | CYP1A1 (0.44) | CYP1A1CYP1B1ERCC5FEN1CYP1A2 | |
| SCHEMBL29326215 | 0.83 | ERCC5 (0.41) | CYP1A1CYP1B1ERCC5FEN1CYP1A2 | |
| SCHEMBL29326183 | 0.83 | ERCC5 (0.43) | CYP1A1CYP1B1ERCC5FEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | CYP1A1 882/4885CYP1B1 1007/4885ERCC5 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.