Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 4/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30469631 | 0.89 | NNMT (0.40) | NNMTITKCSF1RPDE4BGSK3B | |
| SCHEMBL25956895 | 0.89 | NNMT (0.40) | NNMTITKCSF1RPDE4BGSK3B | |
| SCHEMBL24363780 | 0.89 | NNMT (0.40) | NNMTITKCSF1RPDE4BGSK3B | |
| SCHEMBL29347659 | 0.88 | NPC1 (0.38) | PIK3C3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL30469699 | 0.79 | MAPK10 (0.35) | NNMTCSF1RGSK3BALDH1A1MAPT | |
| SCHEMBL24363776 | 0.79 | MAPK10 (0.35) | NNMTCSF1RGSK3BALDH1A1MAPT | |
| SCHEMBL26225781 | 0.75 | JAK2 (0.44) | NNMTSYK | |
| SCHEMBL24365869 | 0.74 | PRMT5 (0.58) | GSK3BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24364044 | 0.74 | PRMT5 (0.58) | GSK3BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24364043 | 0.74 | PRMT5 (0.58) | GSK3BNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | NNMT 1524/4885ITK 4118/4885CSF1R 2230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.