Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.43 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326225 | 0.91 | NPEPPS (0.48) | HSD17B10PKMKDM4ETNKS2NPEPPS | |
| SCHEMBL27378372 | 0.90 | HSD17B10 (0.45) | HSD17B10PKMHPGDKDM4EALDH1A1 | |
| SCHEMBL29326321 | 0.89 | HSD17B10 (0.47) | HSD17B10PKMHPGDKDM4EALDH1A1 | |
| SCHEMBL29326306 | 0.89 | GRIA1 (0.53) | HSD17B10PKMHPGDKDM4EALDH1A1 | |
| SCHEMBL29326360 | 0.88 | HSD17B10 (0.45) | HSD17B10PKMHPGDKDM4EALDH1A1 | |
| SCHEMBL29326358 | 0.87 | HSD17B10 (0.45) | HSD17B10PKMHPGDKDM4EALDH1A1 | |
| SCHEMBL29326440 | 0.85 | NPEPPS (0.43) | HSD17B10PKMKDM4ETNKS2NPEPPS | |
| SCHEMBL29326439 | 0.83 | NPEPPS (0.41) | HSD17B10PKMHPGDKDM4EALDH1A1 | |
| SCHEMBL29326236 | 0.83 | NPEPPS (0.44) | HSD17B10PKMKDM4ETNKS2NPEPPS | |
| SCHEMBL29326756 | 0.81 | HSD17B10 (0.58) | HSD17B10PKMHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | HSD17B10 433/4885PKM 2848/4885HPGD 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.