SCHEMBL29326558

SCHEMBL29326558

COC(=O)[C@@]1(SC)C[C@H](OC(C)=O)[C@@H](NC(=O)COC(C)=O)[C@H]([C@H](OC(C)=O)[C@@H](CNC(=O)Cc2ccc(-c3ccccc3)cc2)OC(C)=O)O1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CD22 P20273 11/20 0.38
▸ MAG P20916 3/20 0.35
▸ LMNA P02545 1/20 0.34
▸ CASP1 P29466 1/20 0.30
▸ CASP3 P42574 1/20 0.30
▸ GAA P10253 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29326540 0.94 CD22 (0.37) CD22MAGLMNACASP1CASP3
SCHEMBL24629760 0.91 CD22 (0.36) CD22MAGLMNAMEN1KMT2A
SCHEMBL24629735 0.91 CD22 (0.36) CD22MAGLMNAMEN1KMT2A
SCHEMBL24630057 0.90 CD22 (0.39) CD22MAGLMNAGAASMN1; SMN2
SCHEMBL29326548 0.89 CD22 (0.38) CD22MAGLMNAGAASMN1; SMN2
SCHEMBL24630238 0.88 CD22 (0.41) CD22MAGLMNA
SCHEMBL31225657 0.87 CD22 (0.33) CD22MAG
SCHEMBL24630237 0.87 CD22 (0.34) CD22MAGLMNA
SCHEMBL24630060 0.87 CD22 (0.34) CD22MAGLMNA
SCHEMBL24630059 0.87 CD22 (0.42) CD22MAGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238422-A1 Hypoimmunogenic Biotherapeutics FCGR3B, CD47, IL2 CD22 18/4885MAG 321/4885LMNA 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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