FCGR3B

Low affinity immunoglobulin gamma Fc region receptor III-B · O75015 · FCGR3B on Sugi Atlas →

334 patent compounds predicted against FCGR3B, 250 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL13917176 SCHEMBL13917176 1.00 1/20
SCHEMBL13421296 SCHEMBL13421296 0.96 1/20
SCHEMBL13917185 SCHEMBL13917185 0.89 1/20
SCHEMBL13921798 SCHEMBL13921798 0.84 1/20
SCHEMBL13420987 SCHEMBL13420987 0.82 1/20
SCHEMBL13420936 SCHEMBL13420936 0.82 1/20
SCHEMBL13421092 SCHEMBL13421092 0.81 1/20
SCHEMBL13917179 SCHEMBL13917179 0.81 1/20
SCHEMBL13421360 SCHEMBL13421360 0.81 1/20
SCHEMBL13421062 SCHEMBL13421062 0.80 1/20
SCHEMBL13917183 SCHEMBL13917183 0.80 1/20
SCHEMBL13917186 SCHEMBL13917186 0.80 1/20
SCHEMBL13917188 SCHEMBL13917188 0.80 1/20
SCHEMBL3200004 SCHEMBL3200004 0.80 1/20
SCHEMBL13921832 SCHEMBL13921832 0.80 1/20
SCHEMBL13420995 SCHEMBL13420995 0.79 1/20
SCHEMBL13921837 SCHEMBL13921837 0.78 1/20
SCHEMBL13421038 SCHEMBL13421038 0.78 1/20
SCHEMBL13921814 SCHEMBL13921814 0.77 1/20
SCHEMBL13421029 SCHEMBL13421029 0.77 1/20

Clinical trials — most relevant to FCGR3B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Immunologic Basis of Anti-IgE Therapy (Study II: On Patients With Asthma) PHASE4COMPLETED
Prospective Double-blind Placebo-controlled Study of the Effect of Xolair (Omalizumab) in Chronic Urticaria Patients PHASE2/PHASE3COMPLETED
Allergic Rhinitis, Immunotherapy and Vitamin d PHASE2/PHASE3UNKNOWN
Rituximab Maintenance Versus Observation After First-line Immunochemotherapy by FCR in Older Patients With Chronic Lymphocytic Leukemia PHASE3COMPLETED
Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma PHASE2COMPLETED
Phase I/II Study of Bendamustine in Combination With Ofatumumab, Carboplatin and Etoposide PHASE1/PHASE2COMPLETED
Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients Better Than Vaccine : An Innovative Treatment PHASE2UNKNOWN
Chemotherapy Sequential Tislelizumab After Radical Resection in Patients With dMMR/MSI-H or POLE/POLD1 Mutations PHASE2NOT_YET_RECRUITING
Lenalidomide With or Without Rituximab After Standard Chemotherapy in Treating Patients With Diffuse Large B-Cell Non-Hodgkin Lymphoma PHASE2COMPLETED
Post IVIG Medication in Children With Immune Thrombocytopenia PHASE1UNKNOWN
Lenalidomide and Dinutuximab With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent Neuroblastoma PHASE1ACTIVE_NOT_RECRUITING
Safety and Efficacy Study of an Anti-CD20 Monoclonal Antibody (AME-133v) to Treat Non-Hodgkin's Lymphoma PHASE1COMPLETED
Preventive IVIG Therapy for Congenital Heart Block EARLY_PHASE1COMPLETED
Frequency of FCGR3A Gene Polymorphisms in Patients With Neuromyelitis Optica Spectrum Disorders, Anti-oligodendrocyte Myelin Protein Antibody Disease, and Multiple Sclerosis. nanRECRUITING
Subclass of Donor-specific Antibody as a Risk Factor of Antibody Mediated Rejection in Renal Transplantation nanCOMPLETED
Does CMV Induced Changes in NK Lymphocyte Biology Influence the Effectiveness of Antibody Therapy Used to Treat B Cell Lymphoproliferative Diseases? nanUNKNOWN
Prognostic Value of CD64 Marker for Patients in Intensive Care Unit nanUNKNOWN
Role of the Neonatal Fc Receptor for IgG in the Pathophysiology of Lupus nanCOMPLETED
Comparison Between Methyl Prednisolone and Intravenous Dexamethazone in Severe Immune Thrombocytopenic Purpra nanUNKNOWN
FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation nanUNKNOWN
sCD163 & CD19 as Candidate Biomarkers in CIDP and MMN nanUNKNOWN
Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer nanRECRUITING
Contribution of Nasal IgE Production to the Boost of Systemic Allergen-specific IgE Upon Nasal Allergen Contact nanRECRUITING
Kinetics of Nasal Cytokine Responses to Mechanical Stimulation nanCOMPLETED
Obinutuzumab in the Management of Idiopathic Membranous Nephropathy nanUNKNOWN
Applying Systems Immunology to the Search for Personalized Biomarkers of Clinical Efficacy nanCOMPLETED
Cytotoxic T Lymphocyte-Associated Antigen-4 (CTLA-4) Gene Single-nucleotide Polymorphism in Primary Immune Thrombocytopenic Purpura in Children nanNOT_YET_RECRUITING
Role of LILRA3 in Ankylosing Spondylitis and Axial Psoriatic Patients nanUNKNOWN
The Effect of Omalizumab on Responses to Cat Allergen Challenge nanCOMPLETED
Correlation Between IgE Parameters and the Response to Omalizumab in Subjects With Severe Asthma nanWITHDRAWN

Related proteins — ESM-2 sequence neighbours (a FCGR3B binder may also engage these)

ProteinNameSimilarity
P08637 1.000 P08637 →
Q09TM2 1.000 Q09TM2 →
Q8SPW2 0.999 Q8SPW2 →
Q09TM4 0.998 Q09TM4 →
E2RP87 0.997 E2RP87 →
A3RFZ7 0.997 A3RFZ7 →
Q9N2I5 0.997 Q9N2I5 →
P27645 0.992 P27645 →
H0VDZ8 0.992 H0VDZ8 →
P79107 0.990 P79107 →
P08508 0.990 P08508 →
A0A0B4J1G0 0.989 A0A0B4J1G0 →
M3XWH1 0.989 M3XWH1 →
P12319 0.988 P12319 →
Q6XPU4 0.987 Q6XPU4 →
Q28942 0.987 Q28942 →
FCGR1A High affinity immunoglobulin gamma Fc receptor I 0.986 landscape →
G1TR84 0.984 G1TR84 →
Q63203 0.984 Q63203 →
Q68SN8 0.983 Q68SN8 →
B6A8C7 0.983 B6A8C7 →
P31995 0.983 P31995 →
Q8SPV8 0.983 Q8SPV8 →
FCGR2A Low affinity immunoglobulin gamma Fc region receptor II-a 0.981 landscape →
P31994 0.981 P31994 →
P26151 0.980 P26151 →
Q60513 0.980 Q60513 →
Q92637 0.979 Q92637 →
G1T7E7 0.979 G1T7E7 →
P0DTI4 0.978 P0DTI4 →