SCHEMBL29326778

SCHEMBL29326778

O=C(CO)N[C@H]1[C@H]([C@H](O)[C@H](O)CO)O[C@@](SCCOCCOCc2cn(CCOCCOCCOCCOCCC(=O)Oc3c(F)c(F)c(F)c(F)c3F)nn2)(C(=O)O)C[C@@H]1O

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SIGLEC7 Q9Y286 1/20 0.37
▸ CD22 P20273 13/20 0.35
▸ MAG P20916 1/20 0.33
▸ NEU2 Q9Y3R4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29326804 1.00 SIGLEC7 (0.37) SIGLEC7CD22MAGNEU2
SCHEMBL29727764 1.00 SIGLEC7 (0.37) SIGLEC7CD22MAGNEU2
SCHEMBL29334798 0.89 CD22 (0.49) CD22MAG
SCHEMBL29727770 0.89 CD22 (0.49) CD22MAG
SCHEMBL29335065 0.89 CD22 (0.49) CD22MAG
SCHEMBL24630005 0.89 SIGLEC7 (0.44) SIGLEC7CD22MAG
SCHEMBL29326848 0.89 SIGLEC7 (0.44) SIGLEC7CD22MAG
SCHEMBL29727743 0.89 SIGLEC7 (0.44) SIGLEC7CD22MAG
SCHEMBL24630000 0.89 SIGLEC7 (0.44) SIGLEC7CD22MAG
SCHEMBL29727731 0.89 CD22 (0.37) SIGLEC7CD22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 — — US disclosed
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238422-A1 Hypoimmunogenic Biotherapeutics FCGR3B, CD47, IL2 SIGLEC7 59/4885CD22 18/4885MAG 321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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