Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16247075 | 1.00 | HCAR2 (0.47) | HCAR2DAOCCNA2CDK2CCNA1 | |
| Hydrochloric Acid SCHEMBL17398190 | 0.98 | HCAR2 (0.46) | HCAR2DAOCCNA2CDK2CCNA1 | |
| SCHEMBL3551909 | 0.98 | HCAR2 (0.49) | HCAR2DAOCCNA2CDK2CCNA1 | |
| SCHEMBL1269829 | 0.94 | HCAR2 (0.53) | HCAR2DAOCCNA2CDK2CCNA1 | |
| SCHEMBL56939 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL17107724 | 0.88 | HCAR2 (0.48) | HCAR2DAOCCNA2CDK2CCNA1 | |
| SCHEMBL12184926 | 0.82 | MKNK1 (0.57) | HCAR2MKNK1MKNK2HCAR3HRH4 | |
| SCHEMBL4016705 | 0.81 | DAO (0.47) | HCAR2DAOCCNA2CDK2CCNA1 | |
| SCHEMBL31080297 | 0.79 | HCAR2 (0.37) | HCAR2MKNK1MKNK2HCAR3 | |
| SCHEMBL27217200 | 0.78 | MKNK1 (0.38) | HCAR2CCNA2CDK2CCNA1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148091-A1 | CDK2 INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2024-07-11 | — | — | WO | disclosed |