Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.38 |
| ▸ | HTR2C | P28335 | 7/20 | 0.38 |
| ▸ | HTR2B | P41595 | 7/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466373 | 0.80 | HTR2C (0.39) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL8236311 | 0.80 | HTR2A (0.39) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL23870387 | 0.79 | HTR2A (0.38) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL29328148 | 0.76 | HTR2C (0.37) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL12533398 | 0.75 | HTR2C (0.38) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL8277854 | 0.73 | MTNR1A (0.40) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL29328231 | 0.73 | HTR2A (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL3006411 | 0.72 | HTR2C (0.35) | HTR2AHTR2CHTR2BKIF11HTR4 | |
| SCHEMBL29413897 | 0.72 | HTR2C (0.35) | HTR2AHTR2CHTR2BKIF11HTR4 | |
| SCHEMBL21872027 | 0.71 | HTR2C (0.43) | HTR2AHTR2CHTR2BMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | HTR2A 2757/4885HTR2C 1491/4885HTR2B 2735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.