Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5535450 | 0.92 | GSK3A (0.47) | GSK3AGSK3BNPBWR1MCHR1PTGS2 | |
| SCHEMBL17995365 | 0.87 | GSK3A (0.45) | GSK3AGSK3BNPBWR1MCHR1PTGS2 | |
| SCHEMBL22197877 | 0.83 | GSK3A (0.47) | GSK3AGSK3BNPBWR1MCHR1PTGS2 | |
| SCHEMBL5575888 | 0.83 | NPBWR1 (0.43) | GSK3AGSK3BNPBWR1MCHR1GAA | |
| SCHEMBL17931792 | 0.81 | GSK3A (0.56) | GSK3AGSK3BNPBWR1MCHR1GAA | |
| SCHEMBL5533650 | 0.81 | GSK3A (0.42) | GSK3AGSK3BTRPV1MAPK1NPSR1 | |
| SCHEMBL25965011 | 0.79 | GSK3A (0.44) | GSK3AGSK3BNPBWR1MCHR1PTGS2 | |
| SCHEMBL25599472 | 0.78 | GSK3A (0.43) | GSK3AGSK3BNPBWR1MCHR1PTGS2 | |
| SCHEMBL15356132 | 0.76 | GSR (0.38) | NPBWR1MCHR1HSP90AA1MAPTHPGD | |
| SCHEMBL18925442 | 0.75 | GSK3A (0.50) | GSK3AGSK3BNPBWR1MCHR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239825-A1 | 1,8-SUBSTITUTED CARBAZOLE-BASED PLATINUM COMPLEXES WITH HIGH RADIATION RATE AND APPLICATION THEREOF | ZHEJIANG HUAXIAN PHOTOELECTRICITY TECHNOLOGY CO., LTD (CN) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239825-A1 | 1,8-SUBSTITUTED CARBAZOLE-BASED PLATINUM COMPLEXES WITH HIGH RADIATION RATE AND APPLICATION THEREOF | LIG3, VIM, TRIM33 | GSK3A 708/4885GSK3B 668/4885NPBWR1 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.