Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K7 | O14733 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940169 | 0.88 | MAPT (0.36) | MAPTMAPK1TDP1FFAR4GAA | |
| SCHEMBL2936433 | 0.85 | MAPT (0.41) | MAPTMAPK1TDP1FFAR4GAA | |
| SCHEMBL2941084 | 0.82 | FFAR4 (0.40) | MAP2K7MAPTFFAR4PTGER4BPTF | |
| SCHEMBL2941456 | 0.82 | BPTF (0.47) | MAP2K7FFAR4NOTUMBPTFPDE10A | |
| SCHEMBL2935952 | 0.82 | NOTUM (0.48) | MAPTMAPK1FFAR4NOTUMALDH1A1 | |
| SCHEMBL2938488 | 0.81 | MAPT (0.44) | MAPTMAPK1TDP1GAAKDM4E | |
| SCHEMBL2942151 | 0.80 | AR (0.41) | FFAR4NOTUMALDH1A1 | |
| SCHEMBL2940816 | 0.79 | BPTF (0.33) | MAP2K7NOTUMPTGER4BPTF | |
| SCHEMBL2935979 | 0.78 | DPP4 (0.46) | FFAR4NOTUMBPTF | |
| SCHEMBL12045685 | 0.78 | ADRB1 (0.46) | MAPTMAPK1TDP1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | claimed |
| WO-2007020565-A1 | OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2007-02-22 | — | — | WO | claimed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | claimed |
| EP-1752192-A1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | Wella Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | claimed |
| EP-1752192-B1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | PROCTER & GAMBLE (US) | 2010-02-03 | — | — | EP | disclosed |
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| WO-2007020565-A1 | OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | disclosed |
| EP-1752192-A1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | Wella Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | TACR1, KRT18, AKR1C4 | MAP2K7 2105/4885MAPT 2140/4885MAPK1 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.