Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.37 |
| ▸ | ITGAL | P20701 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2939478 | 0.82 | SMN1; SMN2 (0.45) | KMT2ASERPINE1SMN1; SMN2HSD11B1MEN1 | |
| SCHEMBL2940469 | 0.81 | KMT2A (0.32) | KMT2AMEN1NOTUMALDH1A1DRD2 | |
| SCHEMBL2934025 | 0.80 | SMN1; SMN2 (0.45) | KMT2ASERPINE1SMN1; SMN2MEN1NOTUM | |
| SCHEMBL2942284 | 0.80 | SMN1; SMN2 (0.45) | KMT2ASERPINE1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL2943119 | 0.77 | CCNE2 (0.46) | KMT2AMEN1ALDH1A1ITGB2ICAM1 | |
| SCHEMBL2976489 | 0.77 | MAPT (0.50) | KMT2ASMN1; SMN2MEN1NOTUMALDH1A1 | |
| SCHEMBL2942979 | 0.76 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL2938201 | 0.76 | SMN1; SMN2 (0.43) | KMT2ASERPINE1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL2936245 | 0.76 | KEAP1 (0.45) | KMT2ASMN1; SMN2MEN1ALDH1A1ITGB2 | |
| SCHEMBL2935899 | 0.75 | CCNE2 (0.37) | KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | claimed |
| WO-2007020565-A1 | OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2007-02-22 | — | — | WO | claimed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | claimed |
| EP-1752192-A1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | Wella Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | claimed |
| EP-1752192-B1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | PROCTER & GAMBLE (US) | 2010-02-03 | — | — | EP | disclosed |
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| WO-2007020565-A1 | OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | disclosed |
| EP-1752192-A1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | Wella Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | TACR1, KRT18, AKR1C4 | KMT2A 2065/4885SERPINE1 2063/4885SMN1; SMN2 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.