SCHEMBL29328357

SCHEMBL29328357

C=Cc1ccc(CS(C)(C)CC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TDP1 Q9NUW8 1/20 0.39
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35
TSHR P16473 1/20 0.34
HDAC8 Q9BY41 2/20 0.34
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
PSMD14 O00487 1/20 0.30
LMNA P02545 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4772456 0.82 ALDH1A1 (0.46) ALDH1A1TDP1CHRNB2CHRNB4CHRNA3
SCHEMBL17278189 0.81 ALDH1A1 (0.50) ALDH1A1TDP1CHRNB2CHRNB4CHRNA3
SCHEMBL8433473 0.80 ALDH1A1 (0.44) ALDH1A1TDP1CHRNB2CHRNB4CHRNA3
SCHEMBL23054273 0.74 ALDH1A1 (0.42) ALDH1A1TDP1CHRNB2CHRNB4CHRNA3
SCHEMBL11832186 0.74 PTPN1 (0.40) ALDH1A1TDP1CHRNB2CHRNB4CHRNA3
SCHEMBL20900454 0.74 ALDH1A1 (0.34) ALDH1A1
SCHEMBL14536541 0.73 ALDH1A1 (0.46) ALDH1A1TDP1TSHRHDAC8TAS1R3
SCHEMBL965172 0.73 TDP1 (0.55) ALDH1A1TDP1TSHRHDAC8TAS1R3
SCHEMBL8434939 0.73 TDP1 (0.50) ALDH1A1TDP1TSHRHDAC8TAS1R3
SCHEMBL15915 0.73 ALDH1A1 (0.58) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151031-A1 BLOCK COPOLYMER, BLOCK COPOLYMER PREPARATION METHOD AND RESIN COMPOSITION 주식회사 엘지화학 2024-07-18 WO disclosed