Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | ABL2 | P42684 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15752003 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1LMNAGLAPMP22 | |
| SCHEMBL11985805 | 0.70 | CCNB2 (0.50) | KDM4EMAPTEGFRABL1PRKCA | |
| SCHEMBL23047217 | 0.69 | PDK2 (0.43) | KDM4EALDH1A1MAPTGAAEGFR | |
| SCHEMBL8324129 | 0.68 | ADORA1 (0.54) | KDM4ELMNAMAPTGAAKMT2A | |
| SCHEMBL1773124 | 0.63 | EGFR (0.36) | EGFRABL1PRKCAABL2 | |
| SCHEMBL25207314 | 0.63 | RET (0.41) | KDM4EALDH1A1MAPTGAAPKM | |
| SCHEMBL30060684 | 0.61 | — | — | |
| SCHEMBL2033970 | 0.61 | — | — | |
| SCHEMBL8802419 | 0.61 | EGFR (0.37) | EGFRABL1PRKCAABL2 | |
| SCHEMBL23332994 | 0.60 | ADK (0.36) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148087-A1 | CDK2 INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2024-07-11 | — | — | WO | disclosed |