Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24742061 | 0.78 | MEN1 (0.38) | ALDH1A1MAPTGAAKDM4EKMT2A | |
| SCHEMBL19434406 | 0.70 | F2RL3 (0.50) | ALDH1A1ALDH1A3MAPTGAAALDH1A2 | |
| SCHEMBL32664232 | 0.70 | MAPK14 (0.44) | ALDH1A1MAPTGAAKDM4EKMT2A | |
| SCHEMBL25283404 | 0.69 | GAA (0.52) | ALDH1A1GAAKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL30079151 | 0.69 | CA1 (0.57) | ALDH1A1MAPTGAAKDM4EKMT2A | |
| SCHEMBL28705905 | 0.68 | MEN1 (0.53) | ALDH1A1ALDH1A3MAPTGAAKDM4E | |
| SCHEMBL31228042 | 0.68 | ALDH1A1 (0.51) | ALDH1A1ALDH1A3MAPTGAAALDH1A2 | |
| SCHEMBL1302416 | 0.68 | ALDH1A1 (0.51) | ALDH1A1ALDH1A3MAPTALDH1A2TLR8 | |
| SCHEMBL11006118 | 0.68 | MAPT (0.56) | ALDH1A1ALDH1A3MAPTLMNARAB9A | |
| SCHEMBL8887061 | 0.67 | ALDH1A1 (0.45) | ALDH1A1MAPTGAAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |