Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14829412 | 0.84 | MEN1 (0.45) | ALDH1A1NR1H2NR1H3MEN1KMT2A | |
| SCHEMBL14829411 | 0.84 | MEN1 (0.45) | ALDH1A1NR1H2NR1H3MEN1KMT2A | |
| SCHEMBL30736727 | 0.82 | NR1H2 (0.47) | ALDH1A1NR1H2NR1H3HPGDHSD17B10 | |
| SCHEMBL24835249 | 0.82 | NR1H2 (0.49) | ALDH1A1NR1H2NR1H3KMT2AHPGD | |
| SCHEMBL14833043 | 0.80 | NPC1 (0.42) | ALDH1A1NR1H2NR1H3MEN1KMT2A | |
| SCHEMBL12988407 | 0.77 | NR1H2 (0.50) | ALDH1A1NR1H2NR1H3MEN1KMT2A | |
| SCHEMBL1653727 | 0.75 | NPC1 (0.52) | ALDH1A1NR1H2NR1H3MEN1KMT2A | |
| SCHEMBL12988409 | 0.75 | NR1H2 (0.50) | ALDH1A1NR1H2NR1H3MEN1KMT2A | |
| SCHEMBL31056656 | 0.75 | NR1H2 (0.46) | NR1H2NR1H3MEN1KMT2AHPGD | |
| Methyl Benzoate SCHEMBL27542747 | 0.74 | TSHR (0.51) | ALDH1A1MEN1KMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |