Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12988407 | 0.86 | NR1H2 (0.50) | NR1H2NR1H3ALDH1A1HDAC1HDAC6 | |
| SCHEMBL30736727 | 0.84 | NR1H2 (0.47) | NR1H2NR1H3KDM4EALDH1A1GAA | |
| SCHEMBL1653727 | 0.83 | NPC1 (0.52) | NR1H2NR1H3KDM4EALDH1A1GAA | |
| SCHEMBL12988409 | 0.83 | NR1H2 (0.50) | NR1H2NR1H3ALDH1A1HDAC1HDAC6 | |
| SCHEMBL5458875 | 0.82 | NPC1 (0.48) | NR1H2NR1H3KDM4EALDH1A1GAA | |
| SCHEMBL29328574 | 0.82 | ALDH1A1 (0.44) | NR1H2NR1H3KDM4EALDH1A1GAA | |
| SCHEMBL29328205 | 0.82 | NR1H2 (0.44) | NR1H2NR1H3KDM4EALDH1A1GAA | |
| SCHEMBL31056656 | 0.81 | NR1H2 (0.46) | NR1H2NR1H3HPGDTSHRHSD17B10 | |
| SCHEMBL29148991 | 0.80 | NR1H2 (0.45) | NR1H2NR1H3KDM4EALDH1A1GAA | |
| SCHEMBL30054126 | 0.80 | NR1H2 (0.45) | NR1H2NR1H3ALDH1A1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360103-A1 | COMPLEMENT INHIBITION | SIXTH STREET LENDING PARTNERS | 2024-10-31 | — | — | US | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| CN-118043314-A | Benzazepine heteroaromatic ring derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-2023020566-A1 | BENZO NITROGEN-CONTAINING HETEROAROMATIC RING DERIVATIVE AND USE THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2023-02-23 | — | — | WO | disclosed |
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360103-A1 | COMPLEMENT INHIBITION | C5, C9, C1QBP | NR1H2 4831/4885NR1H3 4801/4885KDM4E 1096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.