Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236749 | 1.00 | KDM4E (0.35) | KDM4EHSD17B10CYP1A2HIF1AHTT | |
| SCHEMBL29328854 | 0.98 | CYP1A2 (0.35) | KDM4EHSD17B10CYP1A2HIF1AHTT | |
| SCHEMBL19839277 | 0.95 | CYP1A2 (0.35) | KDM4EHSD17B10CYP1A2HIF1AHTT | |
| SCHEMBL31756478 | 0.85 | KDM4E (0.33) | KDM4EHSD17B10CYP1A2HIF1AHTT | |
| SCHEMBL21733525 | 0.83 | TLR4 (0.45) | KDM4EHSD17B10HTTMAPTALDH1A1 | |
| SCHEMBL19839291 | 0.83 | CYP1A2 (0.33) | CYP1A2HIF1AALDH1A1 | |
| SCHEMBL6502942 | 0.80 | GRM5 (0.34) | HTT | |
| SCHEMBL23385946 | 0.79 | CYP1A2 (0.36) | HSD17B10CYP1A2HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29656734 | 0.79 | CYP1A2 (0.36) | HSD17B10CYP1A2HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL523318 | 0.78 | MAPT (0.41) | KDM4ECYP1A2HIF1AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151112-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR | 주식회사 티움바이오 | 2024-07-18 | — | — | WO | disclosed |