SCHEMBL29328854

SCHEMBL29328854

COC(=O)C1CCC2(CCCC2)CC1=O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
HIF1A Q16665 1/20 0.35
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HTT P42858 2/20 0.32
ALDH1A1 P00352 2/20 0.31
KMT2A Q03164 1/20 0.30
BRD4 O60885 1/20 0.30
NPSR1 Q6W5P4 2/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
OPRK1 P41145 1/20 0.30
SCN9A Q15858 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3236749 0.98 KDM4E (0.35) CYP1A2HIF1AKDM4EHSD17B10HTT
SCHEMBL29328852 0.98 KDM4E (0.35) CYP1A2HIF1AKDM4EHSD17B10HTT
SCHEMBL19839277 0.97 CYP1A2 (0.35) CYP1A2HIF1AKDM4EHSD17B10HTT
SCHEMBL19839291 0.84 CYP1A2 (0.33) CYP1A2HIF1AALDH1A1OPRK1GAA
SCHEMBL31756478 0.83 KDM4E (0.33) CYP1A2HIF1AKDM4EHSD17B10HTT
SCHEMBL21733525 0.81 TLR4 (0.45) KDM4EHSD17B10HTTALDH1A1KMT2A
SCHEMBL23385946 0.80 CYP1A2 (0.36) CYP1A2HSD17B10HTTALDH1A1ATM
SCHEMBL29656734 0.80 CYP1A2 (0.36) CYP1A2HSD17B10HTTALDH1A1ATM
SCHEMBL523318 0.79 MAPT (0.41) CYP1A2HIF1AKDM4EHTTALDH1A1
SCHEMBL30015560 0.77 CYP1A2 (0.34) CYP1A2HIF1AKDM4EHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151112-A1 PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR 주식회사 티움바이오 2024-07-18 WO disclosed