Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814840 | 0.89 | GRIK1 (0.41) | GRIK1GRIK2EPHX2EP300CES2 | |
| SCHEMBL28932718 | 0.88 | EPHX2 (0.41) | GRIK1GRIK2EPHX2FFAR3HDAC3 | |
| SCHEMBL8813709 | 0.86 | EP300 (0.43) | EPHX2EP300 | |
| SCHEMBL8462088 | 0.85 | GRIK1 (0.37) | GRIK1GRIK2EPHX2EP300 | |
| SCHEMBL800038 | 0.80 | GRIK1 (0.55) | GRIK1GRIK2FFAR3HDAC3HDAC1 | |
| SCHEMBL811730 | 0.80 | GRIK1 (0.55) | GRIK1GRIK2FFAR3HDAC3HDAC1 | |
| SCHEMBL4246377 | 0.80 | GRIK1 (0.55) | GRIK1GRIK2FFAR3HDAC3HDAC1 | |
| SCHEMBL21635654 | 0.78 | GRIK1 (0.53) | GRIK1GRIK2FFAR3HDAC3HDAC1 | |
| SCHEMBL21635680 | 0.78 | GRIK1 (0.53) | GRIK1GRIK2FFAR3HDAC3HDAC1 | |
| SCHEMBL21635669 | 0.78 | GRIK1 (0.53) | GRIK1GRIK2FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229151-B1 | SALTS OF ACTIVE INGREDIENTS WITH POLYMERIC COUNTER-IONS | BASF SE (DE) | 2012-08-08 | — | — | EP | disclosed |
| EP-2229151-A1 | SALTS OF ACTIVE INGREDIENTS WITH POLYMERIC COUNTER-IONS | BASF SE (DE) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009074609-A1 | SALTS OF ACTIVE INGREDIENTS WITH POLYMERIC COUNTER-IONS | BASF SE (DE) | 2009-06-18 | — | — | WO | disclosed |
| US-4071508-A | SIMULTANEOUS POLYMERIZATION | PLASTOMEDICAL SCIENCES, INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-4036788-A | Anionic hydrogels based on heterocyclic N-vinyl monomers | PLASTOMEDICAL SCIENCES, INC. (US) | 1977-07-19 | — | — | US | disclosed |