⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13950557 | 0.72 | — | — | |
| SCHEMBL21166201 | 0.72 | — | — | |
| SCHEMBL7802950 | 0.70 | — | — | |
| SCHEMBL18365002 | 0.69 | — | — | |
| SCHEMBL22402886 | 0.68 | — | — | |
| SCHEMBL18611771 | 0.68 | — | — | |
| SCHEMBL8962267 | 0.66 | KDM4E (0.30) | — | |
| SCHEMBL22851543 | 0.65 | — | — | |
| SCHEMBL238451 | 0.64 | KDM4E (0.34) | — | |
| SCHEMBL20805252 | 0.64 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036209-B2 | Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides | ARVINAS OPERATIONS, INC. (US) | 2024-07-16 | — | — | US | disclosed |