SCHEMBL8962267

SCHEMBL8962267

CC(C)(C)CCNC(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12284433 0.83
SCHEMBL19373837 0.83
SCHEMBL2600181 0.81 HRH4 (0.34)
SCHEMBL10177795 0.79 HRH4 (0.37)
SCHEMBL19934928 0.79
SCHEMBL238451 0.78 KDM4E (0.34) KDM4EALDH1A1
SCHEMBL19750385 0.77 CYP2C19 (0.39) ALDH1A1
SCHEMBL18591728 0.77 HRH4 (0.39)
SCHEMBL13884336 0.77 HRH4 (0.39)
SCHEMBL18025230 0.77 HRH4 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238212-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2024-07-18 US disclosed
WO-2024126549-A1 SOLUTION FOR POST ETCH RESIDUE REMOVAL (PERR) BASF SE (DE) 2024-06-20 WO disclosed
WO-2024126588-A1 SOLUTION FOR POST ETCH RESIDUE REMOVAL (PERR) BASF SE (DE) 2024-06-20 WO disclosed
US-11820781-B2 Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway NURIX THERAPEUTICS, INC. (US) 2023-11-21 US disclosed
US-20230365610-A1 Aryl Glucoside Derivative SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-11-16 US disclosed
US-20230365610-A1 Aryl Glucoside Derivative SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-11-16 US disclosed
US-11814391-B2 Macrocyclic compounds for the treatment of medical disorders ACHILLION PHARMACEUTICALS, INC. (US) 2023-11-14 US disclosed
US-20230357180-A1 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2023-11-09 US disclosed
US-20230357180-A1 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2023-11-09 US disclosed
US-20230357199-A1 ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS ACHILLION PHARMACEUTICALS, INC. 2023-11-09 US disclosed
US-20080260679-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF ION IMBALANCES RELYPSA, INC. (US) 2008-10-23 US disclosed
US-20080241092-A1 Administering a potassium-binding polymer of a crosslinked ion exchange polymer having acid groups and an alpha/beta electronegative group in a bead form as an oral dosage; renal insufficiency; congestive heart failure; hyperkalemia; high preferential binding capaciity; stability; nonabsorbent; nontoxic RELYPSA, INC. (US) 2008-10-02 US disclosed
US-20080241093-A1 A potassium-binding polymer of a crosslinked ion exchange polymer having acid groups and an alpha/beta electronegative group in a bead form as an oral dosage; renal insufficiency; congestive heart failure; hyperkalemia; high preferential binding capaciity; stability; nonabsorbent; nontoxic RELYPSA, INC. (US) 2008-10-02 US disclosed
US-20080233073-A1 Administering potassium binding polymer of alpha-fluoroacrylic acid comprising counterion of calcium crosslinked with divinylbenzene, (m)ethylenebisacrylamide, N,N'-bis(vinylsulfonylacetyl) ethylene diamine, 1,3-bis(vinylsulfonyl) 2-propanol, vinylsulfone, polyvinyl ether, polyallylether; hyperkalemia RELYPSA, INC. (US) 2008-09-25 US disclosed
US-20080125552-A1 Low-Viscosity Microcapsule Dispersions BASF AKTIENGESELLSCHAFT PATENTS, TRADEMARKS AND LICENSES (DE) 2008-05-29 US disclosed
US-20080103265-A1 Microcapsule Dispersions BASF AKTIENGESELLSCHAFT (DE) 2008-05-01 US disclosed
US-20080064706-A1 Piperidine Derivatives as Histamine H3 Receptor Ligands ASTRAZENECA AB (SE) 2008-03-13 US disclosed
US-20070264505-A1 Resistant to the adsorption of proteins, cells and bacteria; have a chemical chain bonded thereon that comprise a terminal group free of a hydrogen bond donor or where a hydrogen bond donor is sufficiently buried PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-11-15 US disclosed
US-20070249618-A1 Novel Piperidine Derivatives as Histamine H3 Receptor Ligands for Treatment of Depression ASTRAZENECA AB (SE) 2007-10-25 US disclosed
US-7276286-B2 Surfaces that resist the adsorption of biological species PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) 2007-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080260679-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF ION IMBALANCES SLC10A1, SLC9A5, SLC9A3 KDM4E 4372/4885ALDH1A1 2758/4885
US-20080233073-A1 Administering potassium binding polymer of alpha-fluoroacrylic acid comprising counterion of calcium crosslinked with divinylbenzene, (m)ethylenebisacrylamide, N,N'-bis(vinylsulfonylacetyl) ethylene diamine, 1,3-bis(vinylsulfonyl) 2-propanol, vinylsulfone, polyvinyl ether, polyallylether; hyperkalemia KCNH3, KCNAB1, KCNMB1 KDM4E 1050/4885ALDH1A1 2931/4885
US-20080241092-A1 Administering a potassium-binding polymer of a crosslinked ion exchange polymer having acid groups and an alpha/beta electronegative group in a bead form as an oral dosage; renal insufficiency; congestive heart failure; hyperkalemia; high preferential binding capaciity; stability; nonabsorbent; nontoxic KCNN3, ATP6V1B1, KCNK3 KDM4E 1298/4885ALDH1A1 3658/4885
US-20230357199-A1 ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS CFD, TFPI, CFH KDM4E 3553/4885ALDH1A1 2338/4885
US-11820781-B2 Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway BTK, CBL, XIAP KDM4E 1076/4885ALDH1A1 4172/4885
US-20230357180-A1 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION STUB1, MDM2, USP30 KDM4E 1975/4885ALDH1A1 3735/4885
US-20080241093-A1 A potassium-binding polymer of a crosslinked ion exchange polymer having acid groups and an alpha/beta electronegative group in a bead form as an oral dosage; renal insufficiency; congestive heart failure; hyperkalemia; high preferential binding capaciity; stability; nonabsorbent; nontoxic KCNN3, KCNK3, KCNK9 KDM4E 1280/4885ALDH1A1 3581/4885
US-20070249618-A1 Novel Piperidine Derivatives as Histamine H3 Receptor Ligands for Treatment of Depression HRH3, HRH1, HRH4 KDM4E 720/4885ALDH1A1 454/4885
US-20240238212-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS CETP, NPC1, LCAT KDM4E 3784/4885ALDH1A1 4264/4885
US-20230365610-A1 Aryl Glucoside Derivative SLC5A1, SLC5A2, SLC10A1 KDM4E 1703/4885ALDH1A1 514/4885
US-20080064706-A1 Piperidine Derivatives as Histamine H3 Receptor Ligands HRH3, HRH1, HRH4 KDM4E 1044/4885ALDH1A1 451/4885
US-11814391-B2 Macrocyclic compounds for the treatment of medical disorders CFD, TFPI, CFH KDM4E 4570/4885ALDH1A1 4659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.