SCHEMBL29329257

SCHEMBL29329257

OCc1cn(CCn2cc(CO)nn2)nn1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 13/20 0.56
DPP4 P27487 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.47
P2RX7 Q99572 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
ROCK1 Q13464 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
GBA1 P04062 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19509621 0.91 NOTUM (0.53) NOTUMDPP4L3MBTL1P2RX7KDM4E
SCHEMBL21802463 0.89 NOTUM (0.51) NOTUMDPP4L3MBTL1P2RX7KDM4E
SCHEMBL5654651 0.87 NOTUM (0.50) NOTUMDPP4L3MBTL1P2RX7GBA1
SCHEMBL1345911 0.87 DPP4 (0.51) NOTUMDPP4L3MBTL1P2RX7KDM4E
SCHEMBL17084383 0.84 GBA1 (0.51) NOTUMGBA1
SCHEMBL15409578 0.82 NOTUM (0.46) NOTUMDPP4L3MBTL1GBA1
SCHEMBL12788075 0.82 GBA1 (0.57) GBA1
SCHEMBL1345747 0.82
SCHEMBL22807655 0.82
SCHEMBL22044545 0.81 NOTUM (0.45) NOTUMDPP4L3MBTL1P2RX7KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238322-A1 THERAPEUTIC AGENTS AND METHODS OF PRODUCING SAME Glycosynnovations Pty Ltd (AU) 2024-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238322-A1 THERAPEUTIC AGENTS AND METHODS OF PRODUCING SAME SIGLEC7, FUT5, UGCG NOTUM 483/4885DPP4 471/4885L3MBTL1 4652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.