Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19463711 | 0.93 | ALDH1A1 (0.47) | TSHRALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL30910300 | 0.93 | ALDH1A1 (0.47) | TSHRALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL29329260 | 0.93 | TSHR (0.47) | TSHRALDH1A1NPC1LMNATP53 | |
| SCHEMBL28349111 | 0.89 | ALDH1A1 (0.48) | TSHRALDH1A1NPC1MEN1KMT2A | |
| Lithium Ion SCHEMBL19463291 | 0.86 | ALDH1A1 (0.46) | TSHRALDH1A1NPC1MEN1KMT2A | |
| Lithium Ion SCHEMBL30910318 | 0.86 | ALDH1A1 (0.46) | TSHRALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL29329240 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HTTMEN1KMT2ARAB9A | |
| SCHEMBL19463055 | 0.83 | HDAC8 (0.47) | TSHRALDH1A1HTTLMNAKMT2A | |
| SCHEMBL29329256 | 0.80 | MAPT (0.44) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL28346466 | 0.78 | KMT2A (0.47) | TSHRALDH1A1NPC1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |