SCHEMBL29329756

SCHEMBL29329756

Clc1c2c(nc3c(Br)cnn13)C1(CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.32
CHEK1 O14757 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
CCNA1 P78396 1/20 0.31
ABL1 P00519 1/20 0.30
KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29329745 0.94 GSK3B (0.30) GSK3BCHEK1CCNA2CDK2CCNA1
SCHEMBL29329753 0.93 GSK3B (0.30) GSK3B
SCHEMBL29329762 0.80
SCHEMBL29329743 0.80
SCHEMBL29329751 0.79
SCHEMBL29329747 0.78
SCHEMBL29330415 0.78 HPGD (0.31) CHEK1CCNA2CDK2CCNA1
SCHEMBL29329838 0.77
Hydrochloric Acid SCHEMBL30991908 0.76 CDK2 (0.32) CCNA2CDK2CCNA1
SCHEMBL29330416 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151112-A1 PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR 주식회사 티움바이오 2024-07-18 WO disclosed