SCHEMBL29330415

SCHEMBL29330415

Cc1c2c(nc3c(Br)cnn13)C1(CCCC1)CC2

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.31
TSHR P16473 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CHEK1 O14757 1/20 0.30
CCNA2 P20248 1/20 0.30
CDK2 P24941 1/20 0.30
CCNA1 P78396 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29329745 0.84 GSK3B (0.30) CHEK1CCNA2CDK2CCNA1
SCHEMBL29329753 0.83 GSK3B (0.30)
SCHEMBL29330416 0.81
SCHEMBL29329756 0.78 GSK3B (0.32) CHEK1CCNA2CDK2CCNA1
SCHEMBL30991893 0.77 CYP1A2 (0.33) CYP1A2CHEK1CCNA2CDK2CCNA1
SCHEMBL30991926 0.74 CDK2 (0.39) CHEK1CCNA2CDK2CCNA1
Hydrochloric Acid SCHEMBL30991949 0.74 CCNT1 (0.31) CCNA2CDK2CCNA1
SCHEMBL30991971 0.73 CDK9 (0.35) CYP1A2CHEK1CCNA2CDK2CCNA1
SCHEMBL29332445 0.73 CDK9 (0.35) CYP1A2CHEK1CCNA2CDK2CCNA1
SCHEMBL30991888 0.72 IRAK1 (0.35) CCNA2CDK2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151112-A1 PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR 주식회사 티움바이오 2024-07-18 WO disclosed